Constitutively Opa-Expressing and Opa-Deficient Neisseria gonorrhoeae Strains Differentially Stimulate and Survive Exposure to Human Neutrophils
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چکیده
منابع مشابه
Opa - expressing and Opa - deficient Neisseria gonorrhoeae differentially 5 stimulate and survive exposure to human neutrophils 6 7 Louise
1 2 3 4 Constitutively Opa-expressing and Opa-deficient Neisseria gonorrhoeae differentially 5 stimulate and survive exposure to human neutrophils 6 7 Louise M. Ball and Alison K. Criss 8 9 Department of Microbiology, Immunology, and Cancer Biology, 10 University of Virginia Health Sciences Center, Charlottesville, Virginia, USA 11 12 Running title: Gonococcal opa-mediated interactions with neu...
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We investigated the role of gonococcal outer membrane protein PII (also called Opa protein) in nonopsonic adherence to human neutrophils. Gonococcal outer membranes, purified Opa in detergent (Opa), purified Opa in liposomes (Opa+ lips), and peptides composing the second hypervariable (HV2) region of OpaB (strain FA1090) in liposomes (pepHV2 lips) were tested for their abilities to inhibit subs...
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Neisseria gonorrhoeae induces local infections in the human genitourinary tract and can disseminate to other organs to cause severe disease. Blood-derived factors present in the genital mucosa have been suggested to facilitate the spread of N. gonorrhoeae in disseminated gonococcal infections. Using gentamicin invasion assays and confocal microscopy, we observed a strong stimulatory effect of f...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 2013
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.00171-13